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智慧芽:2023年第四代EGFR-C797S抑制剂管线及专利调研报告(29页).pdf

2023-10-15
文档编号:611266
文档页数:29
文档大小:6.57MB
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1、132Contents4EGFREGFRC797SC797SEGFR-TKIsEGFR-C797SEGFR-TKIs5667891011121314151617181920/212223242526EGFR-C797SEGFR3-5271.刘燊.EGFR酪氨酸激酶抑制剂的设计、合成及生物活性筛选和类药性化合物库的构建D.杭州:浙江大学,20152.Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.doi.org/10.1016/j.xinn.2021.10

2、01033.Research on EGFR in gastric cancer and its significance J.Chinese Clinical Oncology,2010,15(2):173-1764.ZD1839(Iressa)induces antiangiogenic effects through inhibition of epidermal growth factor recep-tor tyrosine kinaseJ.Cancer Research,2002,62(9):2554-25605.Immune resistance and EGFR antagon

3、ists in colorectal cancerJ.Cancers,2019,11(8):1089-11056.Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.doi.org/10.1016/j.xinn.2021.100103.7.EGFR mutation incidence in non-small-cell lung cancer of adenocarcinoma histology:a systematic review and globa

4、l map by ethnicityJ.American Journal of Cancer Research,2015,5(9):2892-29118.Rare epidermal growth factor receptor(EGFR)mutations in non-small cell lung cancer.Seminars in Cancer Biology 61(2020)167179.doi.org/10.1016/j.semcancer.2019.09.019.https:/ New Opportunities in Medicinal Chemistry of Fourth-Generation EGFR Inhibitors to Overcome C797S Mutation.doi.org/10.1016/j.ejmech.2020.11299512.Overcoming C797S mutation:The challenges and prospects of the fourth-generation EGFR-TKIs.doi.org/10.1016/j.bioorg.2022.1060572813.https:/

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