Over the last two decades, advances in cellular and solid tumors and hematological malignancies, of which the majority are targeted therapies2 (Exhibit 1a, 1b). accelerated, leading to better characterization of tumor patients, clinicians are now able to offer more biology. Precision oncology, defined as a treatment effectiveness of cancer therapies.3 The future treatment concerns.1 This evolution has driven a shift towards of precision oncology, as evidenced by the modalities greater use of targeted therapeutics in oncology. launched in the U.S since 2015 for the treatment of