CAR T-cell therapies can cause significant side effects, such into the bloodstream, which can cause high fevers, flu-like as cytokine release syndrome, a condition characterized by symptoms, and a dramatic drop in blood pressure. For many excessive immune activation. The hyperactive immune system patients, treatment with steroids can relieve the cytokine can lead to organ toxicity, and immune effector cell-associated release syndrome. However, others require treatment with neurotoxicity syndrome, a neurologic condition that causes confusion, speech dificulties, and seizure, all of which can tocilizumab (Actemra), which blocks a cytokine called IL-6. be potentially life-threatening. Research has shown that in patients affected by cytokine release syndrome, there is an